Pharmacokinetics

Bookboon, 2012. — 147 p. — ISBN 978-87-403-0090-1Contents
ntroduction
ADME and Pharmacokinetics
Absorption: Absorption rate constant, Bioavailability and Salt factor
Distribution: Compartments and Volume of Distribution
Elimination: Elimination rate constant, half-life and clearance
Single intravenous bolus injection into one compartment
Analysis of experimental data from a bolus i.v. injection into one compartment
Single intravenous bolus injection into two compartments
Constant intravenous infusion
Extravascular administration
Multiple dosing
Non-linear pharmacokinetics
Non-compartmental pharmacokinetics
Computerized analysis of pharmacokinetic data
Creatinine clearance
Pharmacokinetic symbols and equations
Additional material available from the internet
Answers to practice questions